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A chemically defined growth medium regularly used for growin
2018-10-24
A chemically-defined growth medium regularly used for growing P. pastoris was previously developed by Invitrogen Inc. (San Diego, CA, USA) and consists of basal salts, a Pichia trace metals (PTM1) solution specifically formulated for Pichia cultures and a carbon source (Invitrogen Corporation, 2002)
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Kearney and Levine present a detailed survey of teenage
2018-10-23
Kearney and Levine (2012) present a detailed survey of teenage childbearing in the US. The main conclusion is that both actual and perceived lack of economic opportunities influence early motherhood. After these factors have been taken into account, teenage motherhood does not appear to cause additi
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br Empirical application public health services supply
2018-10-23
Empirical application: public health services supply Methodology: demand However, to guarantee the robustness of our results, we should divide municipalities into different groups according to at least a different classification other than size. In fact, in Section 7, we use the grouping of mu
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In the current issue of
2018-10-23
In the current issue of E-BioMedicine, report intriguing data to show that very young asymptomatic SCA infants, whilst still producing very high total levels of HbF, demonstrate significant alterations in reticulocyte membrane protein expression, in association with reticulocytosis. The infants with
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According to several studies hotspots of RAS mutations have
2018-10-23
According to several studies, hotspots of RAS mutations have been identified in codons 12, 13, 59, 61, 117, and 146, which are considered to induce conformational changes into constitutively active forms (Prior et al., 2012; Smith et al., 2010). In addition, these gene mutations tend to occur in a m
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In this issue of Kandioler et al analyzed TP mutations
2018-10-23
In this issue of , Kandioler et al. analyzed TP53 mutations which produce a partial functionality of the protein (decreasing its transcriptional activity to less than 75%) in stage III colon cancer patients (). Relevant of this study is that the authors confined their analyses only to stage III pati
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From the identified articles we were
2018-10-23
From the identified articles, we were unable to demonstrate the total comorbidity between bipolar disorder and all anxiety disorders confidently, as some of the individual studies examined only one or two subtypes of the anxiety disorders, e.g. GAD or OCD. However, in twenty-nine out of fifty-two ar
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auda First line anti TB drugs exert
2018-10-23
First-line anti-TB drugs exert their effect by binding directly to the bacterial targets inside the Mycobacterium tuberculosis (Mtb) cells. Only non-protein bound drug concentrations enter bacteria. Therefore, in TB pericarditis each antibiotic must penetrate several layers of tissue to achieve adeq
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Furthermore we show that the induction of TSCM cells is
2018-10-23
Furthermore, we show that the induction of TSCM EZ Cap Reagent GG (3\' OMe) is completely independent from the Wnt signalling pathway. In line with this, the role of Wnt in memory T cell formation has already been called into question by reports about memory T cell formation in CD8+ T cells, in whi
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Dengue is a climate sensitive mosquito borne viral disease
2018-10-23
Dengue is a climate sensitive mosquito-borne viral disease that is generally found in the tropics and subtropics (Murray et al., 2013). According to the World Health Organization (World Health Organization (WHO), 2012) and recent assessment on global burden of diseases (GBD2013) (Murray et al., 2015
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br Children who experience early life seizures prolonged
2018-10-23
Children who experience early life seizures, prolonged febrile convulsions being the most common scenario, often have demonstrable problems with learning and memory later in life (). Although some of the children may go on to have epilepsy (recurrent unprovoked seizures) later in life, the problem
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br Materials and Methods br Results br Discussion
2018-10-23
Materials and Methods Results Discussion As for other diseases and disorders (Marchesi et al., 2015), there is a strong interest in identifying next-generation information to describe how HIV infection impacts the gut environment and the microbiota inhabiting it (Vyboh et al., 2015). The ma
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The following are the supplementary data related
2018-10-23
The following are the supplementary data related to this article. Author Contribution Acknowledgments This study is supported in part by the Bureau of Health Promotion, Department of Health, R.O.C. (Taiwan) (DOH99-HP-1205), Taiwan Ministry of Health and Welfare Clinical Trial and Research Ce
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The lack of such stratification may underlie the inconsisten
2018-10-23
The lack of such stratification may underlie the inconsistent data from trials of LMWH for PMPC (Martinelli et al., 2012; Rodger et al., 2014) due to inclusion of heterogeneous disease mechanisms rather than a focus on those associated with a procoagulant mechanism. These findings also suggest that
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Thus age maturation affects speed of isoniazid acetylation b
2018-10-23
Thus, age (maturation) affects speed of isoniazid acetylation by modifying effect of genotype, a non-linear interaction, however after 5.3years the maturation is complete. Table 4 shows the BFs for NAT2 affinity for isoniazid, or Km. A child\'s height was the primary predictor and had the highest v
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