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Denmark has a long history of establishing nationwide health
2018-10-30
Denmark has a long history of establishing nationwide health care registries and databases with information on all Danish residents (Thygesen and Ersbøll, 2014). Two of the nationwide registries with the highest data quality, the Danish Prescription Registry (initiated in 1995 (Kildemoes et al., 20
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The combination of romidepsin and bryostatin has been shown
2018-10-30
The combination of romidepsin and bryostatin-1 has been shown to be one of the best inducers of latent HIV-1 in primary CD4+ T order AGI-5198 (Laird et al., 2015). However, bryostatin-1 has been showed to be involved in the modulation of NFkB and NFAT (Williams et al., 2004) and romidepsin is known
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Hypothalamic hamartoma HH is a
2018-10-30
Hypothalamic hamartoma (HH) is a rare (about 1:100,000) developmental, non-neoplastic malformation involving the small hypothalamic area located between the infundibular stalk and the mammillary bodies (). HH can be associated with a range of neurological and/or endocrinogical manifestations (). How
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Non small cell lung cancer NSCLC is
2018-10-30
Non-small cell lung cancer (NSCLC) is one of the most common cancers and the leading cause of cancer death worldwide (Siegel et al., 2015). The majority of patients are diagnosed only after the disease has spread beyond the primary site. Thus, systemic chemotherapy, usually with combinations contain
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Linnman et al reanalyzed the NK receptor data
2018-10-30
Linnman et al. (2012) reanalyzed the NK1 receptor data in cWAD patients and healthy controls from an already published study (Linnman et al., 2010). This was done to validate if the NK1 receptor availability was altered in the posterior parietal occipital region as previously reported by others (Lin
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It should be noted that decreased activity
2018-10-29
It should be noted that decreased activity of complex I, decreased coupling and increased ROS production accompany the aging process in many tissues (Table 1), paralleling the increase in the frequency of senescent order fluvastatin in the same tissues (Jurk et al., 2014; Wang et al., 2009). Mitoch
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Tozadenant br Phosphorylated proteins were enriched from
2018-10-29
Phosphorylated proteins were enriched from the total protein extract using the Al(OH)3-MOAC method as previously described with modifications [6]. Approximately 8mg of total protein extract was added to 2g of Al(OH)3. After centrifugation (6000g for 10min), the matrix with retained proteins was wa
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thymidine phosphorylase inhibitor In order to explore the ph
2018-10-29
In order to explore the phenotype of Malpighian tubules associated with mutated Drosophila col4a1 gene, we have chosen a mutant line with the DTS-L3 allele [1–3] as a model, together wild-type OregonR flies. Both lines were incubated at permissive (20°C) and restrictive (29°C) temperatures and evalu
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br Acknowledgements The authors would like to acknowledge th
2018-10-29
Acknowledgements The authors would like to acknowledge the assistance of the University of Nebraska Medical Center Microarray Core Facility for performing the microarrays. The University of Nebraska Microarray Core receives partial support from the National Institute for General Medical Science (
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The present study examines age related differences in ventra
2018-10-29
The present study examines age-related differences in ventral striatal (VS) iFC and dorsal striatal (DS) iFC. This approach permits us to define and contrast the VS iFC and DS iFC networks, which are broadly linked to motivation and cognitive function, respectively (Haber, 2003), and to examine the
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br Neuroimmune mechanisms underlying sex differences Measuri
2018-10-29
Neuroimmune mechanisms underlying sex differences Measuring developmental and life-long effects of ELA exposure produces a moving baseline from which to gauge anatomical and functional differences. Therefore the addition of sex as a factor in developmental studies is challenging. While some anima
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br Introduction It has been long acknowledged
2018-10-29
Introduction It has been long acknowledged that interactions between emotional and cognitive processes are integral to healthy and unhealthy human development (Gray, 2004). Individual differences in cognitive control are thought to reflect variations in neural systems for regulating behavior and
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Yet in spite of the
2018-10-29
Yet, in spite of the increasing number of publications on adults, the neurocognitive mechanisms underlying TO in children are less clear. In a recent study, Johnson and collaborators (Johnson et al., 2015) employed a combined spatio-temporal cueing paradigm and found behavioural evidence that 6–16-y
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br Case report A year old man with
2018-10-29
Case report A 70-year-old man with a medical history of chronic hepatitis B virus without any regular medication presented to our outpatient clinic with generalized purpuric skin eruptions for 1 week. The skin examination revealed generalized palpable purpura with confluence over the scalp, trunk
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Esta dislocaci n provoca una
2018-10-29
Esta dislocación provoca una ruptura con las categorías tradicionales, ya que la “toma” de la plaza pública de Santiago de Chile provoca un quiebre al símbolo de esta civis nacional que impone violentamente la ley o el orden en momentos de toque de queda durante la dictadura chilena. En este espacio
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