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br Acknowledgments br Introduction Mouse embryonic
2018-10-31
Acknowledgments Introduction Mouse embryonic stem (ES) ghrelin receptor can give rise to all somatic cell types and germ cells in a regulative manner and are thereby defined as pluripotent. They are thought to have ‘no pre-determined programme’. However, whether or not an ES cell represents a
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The use of MaSCs from
2018-10-31
The use of MaSCs from GFP mice for in vivo transplant into wild type recipients enabled us to examine the purity of FACS-gated basal and luminal cell populations from the regenerated GFP glands. All epithelial nucleoside transporters (GFP positive) were converged in the CD24+ population, while the
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Neural stem cells in adult rodents are mainly restricted to
2018-10-31
Neural stem cells in adult rodents are mainly restricted to the niches at the subventricular zone (SVZ) in the lateral ventricles and the subgranular zone (SGZ) in the hippocampal dentate gyrus (Doetsch et al., 1999; Palmer et al., 1997; Reynolds and Weiss, 1992; Richards et al., 1992). In the adult
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The following is the supplementary data related to this arti
2018-10-31
The following is the supplementary data related to this article. Author contribution Acknowledgments Introduction Endothelial progenitor insulin receptor (EPCs) circulate in peripheral blood and migrate to a site for vascular formation and repair (Asahara et al., 1997). The pro-angiogenic
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br Materials and methods br Acknowledgements This work was
2018-10-31
Materials and methods Acknowledgements This work was supported by grants from Instituto de Salud Carlos III (PI 15/000227 to MC, Plataforma en Red de Recursos Biomoleculares y BioinformaticosPRB2 PT13/0001/0042) cofunded by FEDER. Resource table. Resource details Loss-of-function mutation
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Cisplatin and Vorinostat alone produced exciting
2018-10-31
Cisplatin and Vorinostat alone produced exciting results, but their combination was extremely efficient in disrupting CSCs and non-CSCs. After 5days of combined therapy, CSCs were completely depleted in HACC2A cells, and a 3.9-fold reduction in CSCs occurred in HACC6 Cy5.5 NHS ester (Fig. 4A and B).
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Collectively these results indicate that both CXCR
2018-10-31
Collectively, these results indicate that both CXCR4 and CXCR7 are necessary for proper differentiation and function of hiPSC-CMs and hECTs, but they might act by separate mechanisms. There have been multiple reports suggesting differential signaling and activity of SDF-1/CXCR4 and SDF-1/CXCR7 pathw
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br Results br Discussion The pluripotency
2018-10-31
Results Discussion The pluripotency status of ES gamma-Secretase inhibitor IX or iPS cells is maintained by a tightly regulated transcription factor network (Boyer et al., 2005). OCT4 is at the center of this network (Pardo et al., 2010; van den Berg et al., 2010) and is associated with chrom
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While we only implemented ArrayEdit for
2018-10-31
While we only implemented ArrayEdit for fluorescence loss and growth rate differences, the method employing HCA is extendable in principle to any image-based phenotype. Phenotypes could be defined by changes in uptake of cytoxicity dyes, live immunocytochemistry for cell surface or extracellular mat
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Collectively we have evaluated the impact of
2018-10-31
Collectively, we have evaluated the impact of a MODY5-causing point mutation (S148L) in the HNF1B gene on human pancreas development using a unique human stem cell model. We report molecular phenotypes (up- and down-regulation of pancreatic genes) when HNF1B is increasingly expressed from days 7 to
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Some of the cultured cardiac MSCs also stained positive for
2018-10-31
Some of the cultured cardiac MSCs also stained positive for the mesodermal progenitor marker TBX18 (Mommersteeg et al., 2010; Christoffels et al., 2006); future studies need to be performed in order to address whether some of the PDGFR-α+ and TBX18+ Afatinib potentially share a developmental origin
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Here are the amplitudes of g harmonics of
2018-10-30
Here are the amplitudes of g-harmonics of the crystal nuclear potential, which are determined by aromatase inhibitor scattering amplitudes for crystal elementary cell (structural amplitudes). In general, are complex values, i.e. =expφ. However, if the crystal is nonabsorbing and centrosymmetric, al
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br Conclusion br Acknowledgements br Introduction Questions
2018-10-30
Conclusion Acknowledgements Introduction Questions about the nature of the education–health gradient are central to social epidemiology and carboxypeptidase b health. The gradient refers to the positive relationship between educational attainment and health (Conti, Heckman & Urzua, 2010) a
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br Background and conceptual framework br Methods br
2018-10-30
Background and conceptual framework Methods Results The first three columns in Table 2 are from OLS models that regressed either physical (Panel A) or mental health (Panel B) on declaring bankruptcy. Model 1 assesses the bivariate relationship of bankruptcy and health, the next model added
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br Materials and methods Adult Cebus apella males from
2018-10-30
Materials and methods Adult Cebus apella males from the Tufted Capuchin Procreation Center (UNESP, Campus Araçatuba) were housed in the same conditions, in individual cages and subjected to natural light-dark (LD) cycles. Eleven monkeys were sacrificed at different times (one animal at each time
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