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Progesterone s metabolite THP may also be mediating burying
2021-07-12
Progesterone's metabolite, 3α,5α-THP, may also be mediating burying and freezing responses. Results show female Long–Evans rats in behavioral estrous have higher P4 levels in serum, Alfacalcidol synthesis and hippocampus compared to diestrous female Long–Evans rats. Additionally, ovx female Long–Eva
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br Activatable photoacoustic probes Photoacoustic PA
2021-07-12
Activatable photoacoustic probes Photoacoustic (PA) imaging is a recently developed technique [47]. The imaging approach uses probes that absorb a pulsed laser beam and convert light energy into acoustic signals. It combines the advantages of the high sensitivity offered by optical imaging and th
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br Halogenases Enzymatic C H activation leading to
2021-07-12
Halogenases Enzymatic C–H activation leading to halogenation is another emerging area in biocatalysis [55,56]. Incorporation of halogen atoms during medicinal chemistry eff ;orts is a well-established practice, presenting an effective means to control the molecule’s bioactivity and physicochemical
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An analysis of EBI expression on dendritic cells
2021-07-12
An analysis of EBI2 expression on dendritic cells (DCs) showed that EBI2 is highly expressed on CD4+ conventional cDCs. In line with this mice deficient for EBI2 largely lack this subset of cDCs in the spleen. Furthermore, the localization of the residual cells is disturbed [10,11]. It was found tha
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MicroRNA miRNA is a class of
2021-07-09
MicroRNA (miRNA) is a class of highly conserved, non-coding small molecules containing 19–25 nucleotides. miRNAs are involved in the regulation of genes associated with cancer development and progression and therefore can act as oncogenes, by contributing to tumor formation,17, 18 or as tumor suppre
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br Materials and methods br Results br
2021-07-09
Materials and methods Results Discussion Ubiquitination is an important eukaryotic process that defines the fate of proteins and their functionality. It has multiple roles in cell survival, differentiation and development (Glickman and Ciechanover, 2002). Ubiquitination is usually known as
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DA neurons are capable of somatodendritic and axonal DA
2021-07-09
DA neurons are capable of somatodendritic and axonal DA release, which may occur at synapses, as well as non-synaptic or asynaptic sites (Trudeau et al., 2014). DA may also be released at different timescales and in response to different DA neuron firing patterns (Grace et al., 2007). Furthermore, s
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br Introduction In mammals there are ten known isoforms of
2021-07-09
Introduction In mammals there are ten known isoforms of the enzyme diacylglycerol kinase (DGK), as well as gene splice variants. Enzymes of this family all have a homologous active site but differ widely in their molecular mass, mechanisms of activation and biological function (Shulga et al., 201
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In cancer interactions between the transformed
2021-07-09
In cancer, interactions between the transformed cancer GSK 2193874 and other cell types recruited to the tumor are important. Tumor associated macrophages provide cancer cells with a suitable low-grade inflammatory milieu including growth promoting factors. Our results suggest a novel pro-tumorige
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WAY-600 Our primary research question is that of the
2021-07-09
Our primary research question is that of the comparative efficacy of accelerated and traditional accounting programs as manifest by success on the CPA exam. We recognize that due to a number of personal and career decisions, not all of those qualified from any of our programs will attempt the CPA ex
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Table gives the list of components which will be modeled
2021-07-09
Table 1 gives the list of components which will be modeled. Transient Voltage Suppressor (TVS) as well as passive elements will be also modeled. For each component, we will choose the EMC (emission and immunity) and transient immunity measurement method adapted to extract the component model. A com
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Estrogen treatment in postmenopausal women requires combinat
2021-07-09
Estrogen treatment in postmenopausal women requires combination with a progestogen in order to prevent endometrial stimulation. This is not necessary, however, with tibolone as progestogenic activity is associated with its Δ4-metabolite that is formed in the liver, as well as locally in the endometr
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br Results and discussions In general experimental analysis
2021-07-09
Results and discussions In general, experimental analysis is time consuming and expensive. Thus, In the present study, Taguchi design of experiments (DOE) was adopted to reduce the number of trials. To analyze the data, a High Level Analysis (HLA) is performed by averaging measured data for each
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Williamson et al interrogated the fusion gene status of
2021-07-09
Williamson et al. [30] interrogated the fusion gene status of 210 appropriately reviewed and annotated RMS specimens divided into three groups: ERMS (n=77); fusion gene-positive ARMS (n=94); and fusion gene-negative ARMS (n=39), the latter comprising a group of tumor samples that appeared histologic
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Apart from the ET system s role
2021-07-09
Apart from the ET system's role in regulating blood vessel tone, it is also involved in a variety of cellular processes that are relevant to DR. For example, the ET receptors influence the survival of retinal ganglion Cilengitide (McGrady et al., 2017; Tonari et al., 2012), development of the retin
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