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The following is the supplementary data related to
2018-11-07
The following is the supplementary data related to this article. Conflicts of Interest Author Contributions Acknowledgements This research was supported, in part, by grants from the National Natural Science Foundation of China (Nos. 81460440, 31670798, 81260322, 81372322 and 81560471), the
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The decrease in blood oxygen saturation correlates with incr
2018-11-07
The decrease in blood oxygen saturation correlates with increased plasma EPO levels in Slc40a1C326S/C326S mice. Hypoxia is the main physiological inducer of EPO production in the kidney via the hypoxia inducible factor HIF2α/HIF1β heterodimer (Haase, 2010). In Slc40a1C326S/C326S mice iron may also d
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br Telomere Dysfunction Can Occur Irrespectively of Length S
2018-11-07
Telomere Dysfunction Can Occur Irrespectively of Length So far, the majority of studies have given evidence to senescence as a result of telomere shortening. However, several reports now suggest that telomere dysfunction can also occur in a length-independent manner (Fig. 1). For example, persist
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br Cecal ligation and puncture h after receiving
2018-11-07
Cecal ligation and puncture 48h after receiving burn or shamburn treatments, rats were anesthetized as described above, followed by the subcutaneous administration of analgesics, buprenorphrine (0.01–0.05mg/kg) and bupivicaine (0.125–0.25%). A 2cm midline incision was made in the rat abdominal ca
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br Data Cross linking formaldehyde and denaturing ethanol an
2018-11-07
Data Cross-linking (formaldehyde) and denaturing (70% ethanol and methanol/glacial acidic acid, 3:1, v/v) fixatives exert different effects on oocyte and NLB morphology (Fig. 1a, a′, a″), large-scale chromatin configuration (b, b′, b″) and on accessibility of the NLB material to immunofluorescenc
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br Acknowledgments This work was supported by
2018-11-07
Acknowledgments This work was supported by Grants from the Giovanni Armenise-Harvard Foundation Career Development Program, the Italian Association for Cancer Research (AIRC) (IG 11786), the Italian Ministry of Health (62/GR-2011-02347880) and the Epigen Flagship Project Grant (Conv. attuativa-So
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On Fig there is typical PCR analysis of five plasmid
2018-11-07
On Fig. 3 there is typical PCR analysis of five plasmid-containing bacterial colonies. The scheme of the experiment was as follows. The DNA fragment of about 900bp was amplified by PCR and cloned in commercial pAL2-T vector (Evrogen). The universal oligonucleotide primers M13dir/M13rev and the worki
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The recorded actions contain br Experimental design
2018-11-07
The recorded actions contain: Experimental design, materials, and methods The MMU VAAC database was recorded with the utmost care and attendance by the author. For avoiding effects of any errors and omissions occurred, all recorded scenes were subject to later inspection while doing the preproce
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Methods br Results br Discussion This study assessed changes
2018-11-07
Methods Results Discussion This study assessed changes in axonal fiber organization over a 2-year period of continued heavy cannabis use in young adults who initiated use during adolescence. White matter microstructure is known to show continued developmental changes during this age period (L
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br Material and methods br Results br Discussion This
2018-11-07
Material and methods Results Discussion This study took a first step at evaluating the comparative neural responses during incentive anticipation among adolescents across the three most prevalent substances of abuse (alcohol, tobacco, and cannabis). We focused on the NAcc, an area within th
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Amygdala reactivity to emotional stimuli in healthy
2018-11-07
Amygdala reactivity to emotional stimuli in healthy young children has been demonstrated (Gee et al., 2013; Todd et al., 2011; Perlman and Pelphrey, 2011), but to date only one has examined its relationship with early childhood psychopathology. A study of face processing in preschool age children wi
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Ecological Momentary Assessment EMA is an ecologically valid
2018-11-07
Ecological Momentary Assessment (EMA) is an ecologically valid method for characterizing emotional reactivity and emotion regulation through repeated in vivo sampling. It entails the gathering of representative real-time data on emotion and behavior in natural environments through the use of signali
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When dural injury occurs and is intraoperatively detected pr
2018-11-06
When dural injury occurs and is intraoperatively detected, primary repair is mandatory. Moreover, the quality of the dura may affect whether primary repair can be performed. It is always necessary to augment the repair with autologous, allogeneic, or synthetic grafts to achieve watertight closure. I
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br Normothermia induced by selective brain
2018-11-06
Normothermia induced by selective phospholipase inhibitor cooling In most review articles, the authors suggest that a target temperature of hypothermia between 32°C and 35°C is beneficial to TBI patients (Table 1). However, Puccio et al showed that normothermia (36–36.5°C) induced by using an int
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Introduction br Minimally invasive mitral valve surgery
2018-11-06
Introduction Minimally invasive mitral valve surgery Mitral valve surgery has been the procedure most greatly influenced by minimally invasive approaches. Several pioneers, like Navia and Cosgrove, Cohn et al, Chitwood et al, and Carpentier et al independently described minimally invasive mitral
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