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br Conclusion Since minimally invasive
2018-10-29
Conclusion Since minimally invasive cardiac surgery was introduced, there has been a significant expansion in popularity and experience. Various techniques for obtaining appropriate exposure have been developed and put into practice. Regardless of the variety of surgical approaches, the overall o
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br Discussion Diagnosing brain tumors in
2018-10-29
Discussion Diagnosing cmv tumors in pregnant women is difficult because the tumor-associated symptoms, including nausea, vomiting, general malaise, and urinary incontinence, are usually nonspecific and are observed among pregnant women with an enlarged gravid uterus. The effects of brain tumors
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Introduction Buried penis is a congenital anomaly in which t
2018-10-29
Introduction Buried penis is a congenital anomaly in which the penis is normal in size but appears to be small (i.e., the external genitalia appear small). Parents of patients with this anomaly or patients themselves visit hospital because of the small appearance of the penis. In addition to the ab
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Introduction Moringa oleifera belonging to the family of Mor
2018-10-29
Introduction Moringa oleifera belonging to the family of Moringaceae is an effective remedy for malnutrition. Moringa is rich in nutrition owing to the presence of a variety of essential phytochemicals present in its leaves, pods and seeds. In fact, moringa is said to provide 7 times more vitamin C
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Our finding that Eng plays a significant role in the
2018-10-29
Our finding that Eng plays a significant role in the EC specification is consistent with the published data that support a role of Eng in vascular development (ten Dijke and Arthur, 2007) and angiogenesis (ten Dijke et al., 2008). It is also consistent with the recent finding that ERG1 induces Eng e
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br Results br Discussion Controlling
2018-10-29
Results Discussion Controlling the chromosome stability of hESCs and their derivatives remains a fundamental challenge in trials of hESC derivative-based cell therapy. In 2004, Andrew and co-workers reported that chromosomal instability during extensive hESC expansion was due to the order Phen
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In this study we demonstrated that
2018-10-29
In this study, we demonstrated that astrocytes exposed to ACM undergo de-differentiation to multipotent NSPCs which can re-differentiate into neurons, astrocytes, and oligodentrocytes. Whereas blockade of Shh biological functions in ACM does not result in astrocyte de-differentiation to multipotent
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In the context of the above studies and several others
2018-10-29
In the context of the above studies and several others PCs are not in all instances dispensable and here the data support an important role of PC in the integrity of the ISC niche. Specifically here the observations indicate a direct dependence of PC on CSF-1R signaling via locally presented CSF-1.
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br Conclusion Our results demonstrate that the GAG mimetic O
2018-10-26
Conclusion Our results demonstrate that the GAG mimetic [OTR4131] is able to enhance the critical human ECFC colony formation frequency, required to improve the amplification of ECFC, and to promote cell properties such as cell adhesion, migration and self-renewal. Moreover, [OTR4131] is able to
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Wnt-C59 Although adult CMs have very limited
2018-10-26
Although adult CMs have very limited proliferative capacity, it has been suggested that a small population of these cells in regions adjacent to a myocardial infarct, retain the ability to divide (Kajstura et al., 1998; Beltrami et al., 2001). Thus, enhancing their proliferation may augment repair i
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Early studies demonstrated that primitive cells are
2018-10-26
Early studies demonstrated that primitive Sephin1 are readily converted into iPSCs (Kim et al., 2008; Kleger et al., 2012; Tsai et al., 2011). Thus, we expected that Lgr5+ cells would be susceptible to reprogramming. Unexpectedly, Lgr5+ cells from HFs and MEFs showed more resistance to early reprog
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As part of the endodermal
2018-10-26
As part of the endodermal lineage, the gallbladder and ventral pancreas both derive from pancreatobiliary progenitors (Spence et al., 2009). The gallbladder is a dispensable organ and can be easily accessed through a minimally invasive laparoscopic procedure. Our previous work demonstrated that mous
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Our analysis revealed that mTOR inhibitors added alone to
2018-10-26
Our analysis revealed that mTOR inhibitors added alone to SF-defined medium can induce mesendoderm, and our follow-up studies confirmed that rapamycin enhances the formation of HE and blood progenitors. Ten-point dose curves revealed a bimodal effect where rapamycin at low concentrations mildly enha
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The ability to use cell surface
2018-10-26
The ability to use cell-surface proteins to specifically sort iPSC-derived hepatocyte-like cells is currently limited. The liver-specific cell-surface protein ASGR1 has been used to sort human ESC- and iPSC-derived hepatocyte-like cells (Basma et al., 2009; Peters et al., 2016). These studies demons
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Much of our knowledge on
2018-10-26
Much of our knowledge on DS comes from the documentation of symptoms in patients and analysis of mouse models. Although the contribution of both sources has been crucial in gaining a better understanding of the syndrome, the molecular pathways leading to the development of DS are still largely unkno
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