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The following is the supplementary data related to this arti
2018-10-31
The following is the supplementary data related to this article. Author contribution Acknowledgments Introduction Endothelial progenitor insulin receptor (EPCs) circulate in peripheral blood and migrate to a site for vascular formation and repair (Asahara et al., 1997). The pro-angiogenic
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br Materials and methods br Acknowledgements This work was
2018-10-31
Materials and methods Acknowledgements This work was supported by grants from Instituto de Salud Carlos III (PI 15/000227 to MC, Plataforma en Red de Recursos Biomoleculares y BioinformaticosPRB2 PT13/0001/0042) cofunded by FEDER. Resource table. Resource details Loss-of-function mutation
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Cisplatin and Vorinostat alone produced exciting
2018-10-31
Cisplatin and Vorinostat alone produced exciting results, but their combination was extremely efficient in disrupting CSCs and non-CSCs. After 5days of combined therapy, CSCs were completely depleted in HACC2A cells, and a 3.9-fold reduction in CSCs occurred in HACC6 Cy5.5 NHS ester (Fig. 4A and B).
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Collectively these results indicate that both CXCR
2018-10-31
Collectively, these results indicate that both CXCR4 and CXCR7 are necessary for proper differentiation and function of hiPSC-CMs and hECTs, but they might act by separate mechanisms. There have been multiple reports suggesting differential signaling and activity of SDF-1/CXCR4 and SDF-1/CXCR7 pathw
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br Results br Discussion The pluripotency
2018-10-31
Results Discussion The pluripotency status of ES gamma-Secretase inhibitor IX or iPS cells is maintained by a tightly regulated transcription factor network (Boyer et al., 2005). OCT4 is at the center of this network (Pardo et al., 2010; van den Berg et al., 2010) and is associated with chrom
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While we only implemented ArrayEdit for
2018-10-31
While we only implemented ArrayEdit for fluorescence loss and growth rate differences, the method employing HCA is extendable in principle to any image-based phenotype. Phenotypes could be defined by changes in uptake of cytoxicity dyes, live immunocytochemistry for cell surface or extracellular mat
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Collectively we have evaluated the impact of
2018-10-31
Collectively, we have evaluated the impact of a MODY5-causing point mutation (S148L) in the HNF1B gene on human pancreas development using a unique human stem cell model. We report molecular phenotypes (up- and down-regulation of pancreatic genes) when HNF1B is increasingly expressed from days 7 to
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Some of the cultured cardiac MSCs also stained positive for
2018-10-31
Some of the cultured cardiac MSCs also stained positive for the mesodermal progenitor marker TBX18 (Mommersteeg et al., 2010; Christoffels et al., 2006); future studies need to be performed in order to address whether some of the PDGFR-α+ and TBX18+ Afatinib potentially share a developmental origin
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Here are the amplitudes of g harmonics of
2018-10-30
Here are the amplitudes of g-harmonics of the crystal nuclear potential, which are determined by aromatase inhibitor scattering amplitudes for crystal elementary cell (structural amplitudes). In general, are complex values, i.e. =expφ. However, if the crystal is nonabsorbing and centrosymmetric, al
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br Conclusion br Acknowledgements br Introduction Questions
2018-10-30
Conclusion Acknowledgements Introduction Questions about the nature of the education–health gradient are central to social epidemiology and carboxypeptidase b health. The gradient refers to the positive relationship between educational attainment and health (Conti, Heckman & Urzua, 2010) a
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br Background and conceptual framework br Methods br
2018-10-30
Background and conceptual framework Methods Results The first three columns in Table 2 are from OLS models that regressed either physical (Panel A) or mental health (Panel B) on declaring bankruptcy. Model 1 assesses the bivariate relationship of bankruptcy and health, the next model added
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br Materials and methods Adult Cebus apella males from
2018-10-30
Materials and methods Adult Cebus apella males from the Tufted Capuchin Procreation Center (UNESP, Campus Araçatuba) were housed in the same conditions, in individual cages and subjected to natural light-dark (LD) cycles. Eleven monkeys were sacrificed at different times (one animal at each time
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br Methods br Results and discussion br Conclusion A very
2018-10-30
Methods Results and discussion Conclusion A very sensitive generic mAb (2G8) against both 3–5 ring unsubstituted and methylated PAHs has been developed through a three-step hybridoma screening procedure. 2G8 has been successfully applied on the KinExA Inline Biosensor for quantifying total
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Optical detection has been thought incapable of measuring ab
2018-10-30
Optical detection has been thought incapable of measuring absolute concentrations of blood components. Therefore, most researchers have employed multicomponent analysis techniques, such as partial least squares or principal component analysis. However, these analysis methods have central contradicti
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and It should be remembered that
2018-10-30
and It should be remembered that the hypothesis to be tested is: the risk of criminal victimization increases as the spending rises, but it reaches a maximum level from which the risk drops as spending levels increase. This hypothesis will not be rejected if coefficients and in the two models speci
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