• Introduction Different responses among the sexes are increas

  2018-10-22

  

  Introduction Different responses among the sexes are increasingly recognized as a major factor in the outcome of patients with trauma and sepsis. In the past years, several animal studies revealed that females had advantageous immunologic and cardiovascular responses during infectious challenges. I

• br Conclusion A hybrid technique combining Dynesys stabiliza

  2018-10-22

  

  Conclusion A hybrid technique combining Dynesys stabilization and interbody fusion can achieve successful interbody fusion, and maintain ROM in the bridged segment and thus improve clinical outcomes. However, it may decrease ROM in the global segment and cause hypermobility in the adjacent segmen

• Natural history of benign prostatic hyperplasia prior to dia

  2018-10-22

  

  Natural history of benign prostatic hyperplasia prior to diagnosis Benign prostatic hyperplasia (BPH) is the most common nonmalignant condition of the prostate developing in aging men. BPH is a major public health concern, causing high morbidity and substantial worsening of men\'s quality of life (

• This study has several limitations

  2018-10-22

  

  This study has several limitations. First, the study has a retrospective and nonrandomized design. The number of peritoneal dialysis patients was relatively small. Consequently, large variations and nonsignificant differences may occur between pre- and postoperative PAS scores in this patient group.

• br Timing of surgery after neoadjuvant chemoradiation therap

  2018-10-22

  

  Timing of surgery after neoadjuvant chemoradiation therapy The optimal timing of interval surgery remains unclear. When a surgeon chooses either short- or long-course RT, surgery should be undertaken within 2 weeks or after 6 weeks, respectively, to avoid severe tissue edema and postoperative mor

• Both CE and AE have recently been included on

  2018-10-22

  

  Both CE and AE have recently been included on the WHO Neglected Tropical disease list. Echinococcosis has a global estimated disease burden of 2–5×107 DALY (Disability Adjusted Life Years) highlighting the considerable medical, social and economic impacts on animal and human populations worldwide (T

• Both CE and AE have recently been included on

  2018-10-22

  

  Both CE and AE have recently been included on the WHO Neglected Tropical disease list. Echinococcosis has a global estimated disease burden of 2–5×107 DALY (Disability Adjusted Life Years) highlighting the considerable medical, social and economic impacts on animal and human populations worldwide (T

• br Materials and methods br Acknowledgments br Introduction

  2018-10-22

  

  Materials and methods Acknowledgments Introduction X chromosome inactivation (XCI) is the mechanism by which dosage compensation of the sex chromosome is achieved in mammals (Leeb and Wutz, 2010). This mechanism is controlled by the noncoding RNA Xist which is expressed from the inactive X

• We differentiated hESCs to the three primary germ layers

  2018-10-22

  

  We differentiated hESCs to the three primary germ layers in this system, identified extracellular biomarker profiles for each, and confirmed germ layer identity with gene expression analysis. A wide variety of extra- and intracellular markers have been previously utilized to identify each of the pr

• br Integrin Expression in Human Stem Cells Integrin expressi

  2018-10-22

  

  Integrin Expression in Human Stem Cells Integrin expression in human embryonic stem buy Plerixafor and selected adult stem cell types is summarised in Table 2. We define here the known expression profiles of integrins on human stem cells of four different types: embryonic, mesenchymal, haematop

• There is a significant need

  2018-10-22

  

  There is a significant need to develop novel therapeutics to counter BoNT poisoning—especially postneuronal internalization (Hakami et al., 2010). However, there are currently no reliable, large-scale cell-based drug screening assays to facilitate such research. This is mainly due to a lack of relev

• Another pathway by which ASCs might

  2018-10-22

  

  Another pathway by which ASCs might improve cardiac outcome is by a paracrine effect, whereby theoretically growth factors, cytokines and signaling molecules produced by the infused stem TAPI-1 Supplier reduce inflammation, and favor the viability of myocytes by inhibiting apoptosis signaling (Uemu

• Ventricular cardiomyocytes VCMs are the most extensively inj

  2018-10-22

  

  Ventricular cardiomyocytes (VCMs) are the most extensively injured cardiac cell type in ischemic heart disease and, as a result, the leading cause of reduced cardiac function. Therefore, it is of great interest to generate a renewable source of VCMs from ESCs for cell-based therapies to treat heart

• br Methods br Results br Discussion We have developed

  2018-10-22

  

  Methods Results Discussion We have developed a serum-free method for the efficient generation of near pure populations of human ECs from hESCs and demonstrated the flexibility and utility of this system in identifying molecules that modulate endothelial phenotype. CD34+KDR+ hematovascular m

• Dinitrophenol DNP is well known

  2018-10-22

  

  2,4-Dinitrophenol (DNP) is well known to be cytotoxic at high concentrations. However, recent studies have demonstrated that at low micromolar, non-toxic concentrations, DNP has neuroprotective properties in a number of in vitro and in vivo models of neurodegeneration (reviewed in (De Felice and Fer

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